Antibody

Amyloid Beta (4G8)

Tools

Back to the Top

Clonality: monoclonal
Host: Mouse
Isotype: IgG2b
Source: Chemicon and Upstate are Millipore
Cat# MAB1561
References:
He, 2009
O'Connor, 2008
Chang, 2007
Formulation: purified Ig, liquid, PBS, thimerosal
Reactivity:
Reacts in: Dog, Human
others not tested

Immunogen/Epitope

immunogen = amyloid-β, juxtamembrane EC domain, aa 17-24; epitope lies between aa 18-22

Specificity

reactive to amyloid-β, aa 17-24

Comments / Questions

No Available Comments

Make a comment or submit a question

To make a comment you must login or register.

References

Paper Citations

  1. He P, Shen Y. Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci. 2009 May 20;29(20):6545-57. PubMed.
  2. O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, Hébert SS, De Strooper B, Haass C, Bennett DA, Vassar R. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron. 2008 Dec 26;60(6):988-1009. PubMed.
  3. Chang WP, Downs D, Huang XP, Da H, Fung KM, Tang J. Amyloid-beta reduction by memapsin 2 (beta-secretase) immunization. FASEB J. 2007 Oct;21(12):3184-96. PubMed.

Further Reading