Antibody
GFAP (G-A-5)
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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: Sigma Aldrich
cat# C9205
References:
Liu, 2009
(unspecified formulation)
Anderson, 2008
Sun, 2001
Formulation: PBS, BSA, azide, purified, Cy3 conj
Reactivity:
Reacts in: Cat, Chicken, Pig, Human, Rat
not in Bergmann glia, goldfish, octopus and snail
Immunogen/Epitope
purified porcine spinal cord GFAP (epitope localized on the carboxy terminal Cys II fragment of GFAP and the N-terminal part of the tail sequence of the molecule)
Specificity
50 kDa GFAP in brain and spinal cord, but not with other intermediate filaments
Note
double labeling
References
Paper Citations
- Liu B, Rasool S, Yang Z, Glabe CG, Schreiber SS, Ge J, Tan Z. Amyloid-peptide vaccinations reduce {beta}-amyloid plaques but exacerbate vascular deposition and inflammation in the retina of Alzheimer's transgenic mice. Am J Pathol. 2009 Nov;175(5):2099-110. PubMed.
- Anderson JM, Hampton DW, Patani R, Pryce G, Crowther RA, Reynolds R, Franklin RJ, Giovannoni G, Compston DA, Baker D, Spillantini MG, Chandran S. Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis. Brain. 2008 Jul;131(Pt 7):1736-48. PubMed.
- Sun Y, Nadal-Vicens M, Misono S, Lin MZ, Zubiaga A, Hua X, Fan G, Greenberg ME. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell. 2001 Feb 9;104(3):365-76. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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