Antibody

APP

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Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: A B R - Thermo Scientific
Cat# OPA1-01132
Reference:
Liu, 2009
Formulation: purified IgG, PBS, azide
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

immunogen = aa 653-662 from human amyloid A4 precursor protein and amino acids 1-10 from Abeta (completely conserved in rabbit, pig, bovine,guinea pig, and chicken)

Specificity

APP and beta amyloid

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References

Paper Citations

  1. . Amyloid-peptide vaccinations reduce {beta}-amyloid plaques but exacerbate vascular deposition and inflammation in the retina of Alzheimer's transgenic mice. Am J Pathol. 2009 Nov;175(5):2099-110. PubMed.

Further Reading