Lv S, Zhang Y, Lin Y, Fang W, Wang Y, Li Z, Lin A, Dai X, Ye Q, Zhang J, Chen X. ApoE4 exacerbates the senescence of hippocampal neurons and spatial cognitive impairment by downregulating acetyl-CoA level. Aging Cell. 2023 Sep;22(9):e13932. Epub 2023 Aug 18 PubMed.

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Research Models

  1. APOE3 Targeted Replacement