Suzuki R, Takahashi H, Yoshida C, Hidaka M, Ogawa T, Futai E. Specific Mutations near the Amyloid Precursor Protein Cleavage Site Increase γ-Secretase Sensitivity and Modulate Amyloid-β Production. Int J Mol Sci. 2023 Feb 16;24(4) PubMed.

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Mutations

  1. APP T714I (Austrian)
  2. APP V717I (London)