Chiu MJ, Yang SY, Horng HE, Yang CC, Chen TF, Chieh JJ, Chen HH, Chen TC, Ho CS, Chang SF, Liu HC, Hong CY, Yang HC. Combined plasma biomarkers for diagnosing mild cognition impairment and Alzheimer's disease. ACS Chem Neurosci. 2013 Dec 18;4(12):1530-6. Epub 2013 Oct 23 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
Aβ40
(Plasma)		 AD
(30)		 48.91 ± 29.7
pg/mL §		 Immunomagnetic Reduction;
Other/Not Specified;
In-house		 McKhann et al., 2011
Aβ40
(Plasma)		 AD
(31)		 38.27 ± 9.15
pg/mL §		 Immunomagnetic Reduction;
Other/Not Specified;
In-house		 McKhann et al., 2011
Aβ40
(Plasma)		 CTRL-
CNC
(107)		 71.44 ± 30.75
pg/mL §		 Immunomagnetic Reduction;
Other/Not Specified;
In-house
Aβ42
(Plasma)		 AD
(30)		 28.15 ± 25.64
pg/mL §		 Immunomagnetic Reduction;
Other/Not Specified;
In-house		 McKhann et al., 2011
Aβ42
(Plasma)		 AD
(31)		 18.61 ± 1.55
pg/mL §		 Immunomagnetic Reduction;
Other/Not Specified;
In-house		 McKhann et al., 2011
Aβ42
(Plasma)		 CTRL-
CNC
(107)		 15.29 ± 1.6
pg/mL §		 Immunomagnetic Reduction;
Other/Not Specified;
In-house
tau-total
(Plasma)		 AD
(30)		 73.01 ± 139.38
pg/mL §		 Immunomagnetic Reduction;
Other/Not Specified;
In-house		 McKhann et al., 2011
tau-total
(Plasma)		 AD
(31)		 53.57 ± 22.87
pg/mL §		 Immunomagnetic Reduction;
Other/Not Specified;
In-house		 McKhann et al., 2011
tau-total
(Plasma)		 CTRL-
CNC
(107)		 16.16 ± 9.09
pg/mL §		 Immunomagnetic Reduction;
Other/Not Specified;
In-house

§ Data supplied to Alzforum by author

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : Aβ40 (Plasma and Serum)
  2. CTRL vs AD : Aβ40 (Plasma and Serum)
  3. AD vs CTRL : Aβ42 (Plasma and Serum)
  4. CTRL vs AD : Aβ42 (Plasma and Serum)
  5. AD vs CTRL : tau-total (Plasma and Serum)
  6. CTRL vs AD : tau-total (Plasma and Serum)