Perneczky R, Guo LH, Kagerbauer SM, Werle L, Kurz A, Martin J, Alexopoulos P. Soluble amyloid precursor protein β as blood-based biomarker of Alzheimer's disease. Transl Psychiatry. 2013 Feb 19;3:e227. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : sAPPα (Plasma and Serum)
- CTRL vs AD : sAPPα (Plasma and Serum)
- AD vs CTRL : sAPPβ (Plasma and Serum)
- CTRL vs AD : sAPPβ (Plasma and Serum)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| sAPPα (Plasma) |
AD (80) |
18.24 ± 17.9 ng/mL |
ELISA; Other/Not Specified; Immuno-Biological Laboratories |
McKhann et al., 1984 |
| sAPPα (Plasma) |
CTRL- CNC (37) |
9.37 ± 1.6 ng/mL |
ELISA; Other/Not Specified; Immuno-Biological Laboratories |
|
| sAPPβ (Plasma) |
AD (80) |
3.94 ± 4.36 ng/mL |
ELISA; Other/Not Specified; Immuno-Biological Laboratories |
McKhann et al., 1984 |
| sAPPβ (Plasma) |
CTRL- CNC (37) |
5.73 ± 0.94 ng/mL |
ELISA; Other/Not Specified; Immuno-Biological Laboratories |
Recommends
Please login to recommend the paper.
Comments
No Available Comments
Make a Comment
To make a comment you must login or register.