Jicha GA, Berenfeld B, Davies P.
Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease.
J Neurosci Res. 1999 Mar 15;55(6):713-23.
PubMed.
This antibody recognizes a folded conformation of tau containing amino acids 2-10 and 312-342. We have used it successfully to detect misfolded tau in mouse models of tauopathy using array tomography, a relatively new imaging technique (Kopeikina et al., 2013).
References:
Kopeikina KJ, Polydoro M, Tai HC, Yaeger E, Carlson GA, Pitstick R, Hyman BT, Spires-Jones TL.
Synaptic alterations in the rTg4510 mouse model of tauopathy.
J Comp Neurol. 2013 Apr 15;521(6):1334-53.
PubMed.
Comments
University of Edinburgh
References:
Kopeikina KJ, Polydoro M, Tai HC, Yaeger E, Carlson GA, Pitstick R, Hyman BT, Spires-Jones TL. Synaptic alterations in the rTg4510 mouse model of tauopathy. J Comp Neurol. 2013 Apr 15;521(6):1334-53. PubMed.
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