Illes-Toth E, Meisl G, Rempel DL, Knowles TP, Gross ML. Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants. ACS Chem Neurosci. 2021 Jun 2;12(11):1972-1982. Epub 2021 May 14 PubMed.

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Mutations

  1. APP A692G (Flemish)
  2. APP E693G (Arctic)
  3. APP E693K (Italian)
  4. APP E693Q (Dutch)
  5. APP D694N (Iowa)