Serrano-Pozo A, Das S, Hyman BT. APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches. Lancet Neurol. 2021 Jan;20(1):68-80. PubMed.

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Mutations

  1. APOE C130R (ApoE4)
  2. APOE R176C (ApoE2)