Antibody

Tau, 4-repeat section

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Clonality: polyclonal
Host: Rabbit
Source: K9JA
(E-M. Mandelkow, Max-Planck-Unit for Struct. Mol. Biol).  This antibody is avaliable from DAKO as A0024
Reference:
Wang, 2007
Reactivity:
Reacts in: Human

Immunogen/Epitope

epitope comprises the 4 repeats of Tau, starting at Q244 (preceded by M) and extends to the C-terminus (L441)

Specificity

recognizes the 4-repeat section of tau; binds very tightly

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References

Paper Citations

  1. Wang YP, Biernat J, Pickhardt M, Mandelkow E, Mandelkow EM. Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10252-7. PubMed.

External Citations

  1. E-M. Mandelkow

Further Reading

No Available Further Reading