. Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease. J Exp Med. 2007 Aug 6;204(8):1999-2008. PubMed.

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  1. There is increasing evidence that fibrinogen/fibrin may directly interact with the CR3 cd11/cd18b (mac1) receptor on microglial cells and regulate their state of activation. These new findings suggest that fibrin deposition may be an important target in AD.

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