CONFERENCE COVERAGE SERIES
LATE (Limbic-predominant Age-related TDP-43 Encephalopathy) 2022
Online Meeting
11 February 2022
Virtual Workshop Tackles LATE, a Cause of Late-life Dementia
At LATE 2022, researchers hashed out neuropathological and clinical characteristics of limbic predominant age-related TDP-43 encephalopathy, a major contributor to late-life cognitive decline and potential bungler of AD clinical trials.
Scientists Say LATE Worsens Cognitive Decline
Limbic predominant age-related TDP-43 encephalopathy is strikingly common among octo- and nonagenarians, and it causes their cognition to slide. LATE dramatically boosts the risk of dementia among people who also have plaques and tangles.
Does LATE Subvert Alzheimer's Trials? Biomarkers, Please!
Limbic TDP-43 pathology accelerates cognitive decline in people with or without AD. Exosome and imaging biomarkers look promising.