Jobs
Postdoctoral position – Environmental exposure in Parkinson’s disease
Posted 13 Nov 2024
Employer
Université Laval
Location
Quebec, Canada
Principal Investigator
Contact
For more information, please contact Dr. Aurélie de Rus Jacquet: aurelie.jacquet@crchudequebec.ulaval.ca.
Applications will be reviewed regularly until the position is filled.
Candidates selected for an interview will be contacted. Interested candidates are invited to send the following documents in PDF format to Dr. Aurélie de Rus Jacquet:
- A CV describing your academic background, research experience, skills, awards, and publications
- A cover letter describing your previous experience, career goals and research interests
- Names and e-mail addresses of three people who can provide letters of recommendation
Description
The research team specializes in the study of Parkinson's disease and aims to describe the molecular mechanisms regulating disease progression. Dr. de Rus Jacquet studies the role of glial cells in disease pathogenesis and the mechanisms by which they regulate cellular interactions at the blood-brain barrier. We use induced pluripotent stem cell-based models and microfluidic technologies to study cellular interactions and describe the mechanisms underlying Parkinson’s disease (www.derusjacquetlab.com).
The project:
The project will focus on understanding the contributions of environmental contaminants to blood-brain barrier dysfunction and neurodegeneration in Parkinson's disease. The objective is to identify new disease triggers and propose innovative therapeutic approaches to slow or halt disease progression. Methodological approaches heavily rely on iPSC cell culture and directed differentiation toward specialized cell types, along with ex vivo patient samples and postmortem tissue.
The lab is located in a dynamic and constantly evolving work environment. Its members strive to offer a workplace where everyone can grow and explore their scientific creativity. The working languages are English and French. Université Laval is a French-speaking university.
Requirements
- Ph.D. in neurosciences, molecular and cell biology, or a related background
- Cell culture expertise is an asset
- Work independently and as part of a team
- Highly motivated
- Dynamic, curious and eager to improve patients' health
- Available to start between January and February 2025