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Notice of Special Interest (NOSI): Alzheimers and Alzheimers-related Dementias (AD/ADRD) Focused Competitive Revisions to Existing NIH Grants that are not focused on AD/ADRD (NOT-AG-24-073)

Sponsor: National Institutes of Health

Award: Applications for this initiative must be submitted using the following opportunity or its subsequent reissued equivalent: PA-23-317- Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)

Due Date: This notice applies to due dates on or after March 6, 2025 and subsequent receipt dates through March 7, 2025.

Notice of Special Interest (NOSI): Genetic Underpinnings of Endosomal Trafficking as a Pathological Hub in Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (NOT-AG-24-029)

Sponsor: National Institute on Aging

Award: Submit applications for this initiative using one of the following notices of funding opportunities (NOFOs) or any reissues of these announcements through the expiration date of this notice: PAR-25-331 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Not Allowed); PAR-25-332 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional)

Due Date: This notice applies to due dates on or after March 11, 2025 and subsequent receipt dates through November 17, 2027.

Notice of Special Interest (NOSI): Common Mechanisms and Interactions Among Neurodegenerative Diseases (NOT-AG-24-031)

Sponsor: National Institute on Aging

Award: Submit applications for this initiative using one of the following notices of funding opportunities (NOFOs) or any reissues of these announcements through the expiration date of this notice: PAR-25-331 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional); PAR-25-332 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional).

Due Date: This notice applies to due dates on or after March 11, 2025 and subsequent receipt dates through November 17, 2027.

Notice of Special Interest (NOSI): Understanding Alzheimer's Disease in the Context of the Aging Brain (NOT-AG-24-032)

Sponsor: National Institute on Aging

Award: Submit applications for this initiative using one of the following notices of funding opportunities (NOFOs) or any reissues of these announcements through the expiration date of this notice: PAR-25-331 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional); PAR-25-332 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional).

Due Date: This notice applies to due dates on or after March 11, 2025 and subsequent receipt dates through November 17, 2027.

Notice of Special Interest (NOSI): Selective Cell and Network Vulnerability in Aging and Alzheimers Disease (NOT-AG-24-033)

Sponsor: National Institute on Aging

Award: Submit applications for this initiative using one of the following notices of funding opportunities (NOFOs) or any reissues of these announcements through the expiration date of this notice: PAR-25-331 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional); PAR-25-332 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional)

Due Date: This notice applies to due dates on or after March 11, 2025 and subsequent receipt dates through November 17, 2027.

Notice of Special Interest (NOSI): Major Opportunities for Research in Epidemiology of Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD) and Cognitive Resilience (NOT-AG-24-042)

Sponsor: National Institute on Aging

Award: Submit applications for this initiative using one of the following notice of funding opportunity (NOFO) or any reissues of these announcements through the expiration date of this notice: PAR-25-331 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional); PAR-25-332 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional)

Due Date: This notice applies to due dates on or after March 11, 2025 and subsequent receipt dates through November 17, 2027.

Notice of Special Interest (NOSI): Novel Approaches to Characterizing and Diagnosing Alzheimer's Disease and Related Dementias (NOT-AG-24-030)

Sponsor: National Institute on Aging

Award: Submit applications for this initiative using one of the following notices of funding opportunities (NOFOs) or any reissues of these announcements through the expiration date of this notice: PAR-25-331 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional); PAR-25-332 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional)

Due Date: This notice applies to due dates on or after March 11, 2025 and subsequent receipt dates through November 17, 2027 .

Notice of Special Interest (NOSI): Human Cell Biology of Alzheimer's Disease Genetic Variants (NOT-AG-24-039)

Sponsor: National Institute on Aging

Award: Submit applications for this initiative using one of the following notice of funding opportunity (NOFO) or any reissues of these announcements through the expiration date of this notice: PAR-25-331 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional); PAR-25-332 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional).

Due Date: This notice applies to due dates on or after March 11, 2025 and subsequent receipt dates through November 17, 2027.

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