Notice of Special Interest (NOSI): National Institute of General Medical Sciences Predoctoral Basic Biomedical Sciences Research Training Program (T32) (NOT-GM-24-056)

Sponsor: National Institute Health

Due Date: First Available Due Date: January 25, 2025. Expiration Date: September 26, 2026.

Human Brain Single-cell Genomics Explorer (U24 - Clinical Trial Not Allowed) (RFA-NS-24-038)

Sponsor: National Institutes of Health

Award: Annual direct costs may not exceed $1M. The maximum project duration for this Pilot Project is 3 years.

Due Date: Letter of Intent due January 14, 2025. Application due February 14, 2025.

Notice of Special Interest (NOSI): Ruth L. Kirschstein NRSA Fellowship Awards to Support Training in Research Related to Down Syndrome as Part of the INCLUDE Project (NOT-OD-24-143)

Sponsor: National Institutes of Health

Due Date: This notice applies to due dates on or after December 8, 2024 and subsequent receipt dates through September 8, 2027.

Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U01 Clinical Trial Optional) (PAR-25-055)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Multiple due dates; see announcement.

Centers on the Demography and Economics of Aging, Including Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD) (D&E Centers) (P30 Clinical Trial Optional) (RFA-AG-25-007)

Sponsor: National Institute on Aging

Due Date: Letter of Intent due December 10, 2024. Application due January 10, 2025.

Centers on the Demography and Economics of Aging and Alzheimers Disease and Alzheimers Disease-Related Dementias Coordinating Center (U24 Clinical Trial Optional) (RFA-AG-25-008)

Sponsor: National Institute on Aging

Due Date: Letter of Intent due December 10, 2024. Application due January 10, 2025.

Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders(U01 Clinical Trial Optional) (PAR-25-050)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Multiple due dates; see announcement.

Notice of Special Interest (NOSI): The Role of the Immune System in Aging Brain and Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (NOT-AG-24-010)

Sponsor: National Institute on Aging, National Institute of Allergy and Infectious Diseases

Award: This initiative relates to the following notices of funding opportunities (NOFOs): PAR-22-093 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01 Clinical Trial Optional); PAR-22-094 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional).

Due Date: This notice applies to due dates on or after November 12, 2024 and subsequent receipt dates through December 31, 2027.

NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) (PA-25-080)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed) (RFA-NS-25-018)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required) (RFA-NS-25-024)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Application due January 24, 2025. Letter of intent due 30 days prior to application.

Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional) (PAR-25-051)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed) (RFA-MH-26-120)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed) (RFA-NS-25-017)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

Administrative Supplements to Promote Diversity in Research and Development Small Businesses SBIR/STTR (Admin Supp Clinical Trial Not Allowed) (PA-24-255)

Sponsor: National Institutes of Health, Centers for Disease Control and Prevention

Award: Individual(s) must have support under an active grant or cooperative agreement, and the research proposed in the supplement must be accomplished within the competitive segment of the active award. Application budgets are limited to no more than the amount of the current parent award. The project and budget periods must be within the currently approved project period for the existing parent award.

Due Date: Applications are accepted on a rolling basis at any time starting 30 days after the Open Date (varies by IC) until the expiration date (October 14, 2027).