Analytical and Clinical Validation of Biomarkers for Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (U01 Clinical Trial Optional) (PAR-25-209)

Sponsor: National Institute on Aging

Due Date: Multiple due dates; see announcement.

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) (RFA-MH-26-170)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

NINDS Exploratory Clinical Trials (UG3/UH3 Clinical Trial Required) (PAR-25-054)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: February 10, 2025. Letter of Intent due 30 days prior to application.

NINDS Ruth L. Kirschstein National Research Service Award (NRSA) for Training of Postdoctoral Fellows (F32 Clinical Trial Not Allowed) (PAR-25-234)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Multiple due dates; see announcement.

Research Opportunities for New and "At-Risk" Investigators to Promote Workforce Diversity (R01 Clinical Trial Optional) (PAS-25-190)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed) (PAR-25-225)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Multiple due dates; see announcement.

Engineering Next-Generation Human Nervous System Microphysiological Systems (R01 Clinical Trials Not Allowed) (PAR-25-198)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed) (PAR-25-199)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

Research Infrastructure Development for Interdisciplinary Aging Studies (R61/R33 - Clinical Trial Optional) (PAR-25-218)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

Advanced-Stage Development and Utilization of Research Infrastructure for Interdisciplinary Aging Studies (R33 Clinical Trial Optional) (PAR-25-219)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

NIA Multi-site Clinical Trial Implementation Grant (R01 Clinical Trial Required) (PAR-25-222)

Sponsor: National Institute on Aging

Due Date: Multiple due dates; see announcement.

Bioengineering Partnerships with Industry (U01 Clinical Trial Optional) (PAR-24-325)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional) (PAR-25-036)

Sponsor: National Institute of Mental Health, National Institute on Aging

Due Date: Multiple due dates; see announcement.

NIA Academic Leadership Career Award (K07 Independent Clinical Trial Not Allowed) (PAR-24-321)

Sponsor: National Institute on Aging

Due Date: Multiple due dates; see announcement.

NINDS Sustainable Transformation of Institutional Research Rigor (STIRR) Program (RC2 - Clinical Trial Not Allowed) (RFA-NS-25-019)

Sponsor: National Institute of Neurological Disorders and Stroke

Award: Application budgets need to reflect the actual needs of the proposed project; however, it is anticipated that most awards will be between $150,000-$800,000 direct costs per year, commensurate with the scope of the proposed program. The maximum project period is 3 years.

Due Date: Application due October 17, 2025. Letter of intent due 30 days prior to application.