Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Required) (PAR-25-216)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Multiple due dates; see announcement.

Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trial Not Allowed) (PAR-25-214)

Sponsor: National Institutes of Health

Award: No more than $200,000 direct costs may be requested in any single year. The combined budget may not exceed $275,000 direct costs for the two-year project period.

Due Date: Multiple due dates; see announcement.

BRAIN Initiative: Promoting Equity Through BRAIN Technology Partnerships (R34 - Clinical Trials Not Allowed) (RFA-NS-25-016)

Sponsor: National Institutes of Health

Award: Direct costs limited to $225,000 per year and $450,000 over the 3-year project period.

Due Date: June 17, 2025; June 17, 2026. Letter of intent due 30 days prior to application.

Limited Competition: NIH Neuroscience Doctoral Readiness Program (DR. Program) (R25 Clinical Trial Not Allowed) (RFA-NS-25-027)

Sponsor: National Institute of Neurological Disorders and Stroke, National Institute on Drug Abuse

Due Date: March 25, 2025.

Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional) (PAR-25-065)

Sponsor: National Institute on Aging, National Institute of Mental Health

Due Date: Multiple due dates; see announcement.

Seamless Early-Stage Clinical Drug Development for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required) (PAR-25-226)

Sponsor: National Institute on Aging

Due Date: Multiple due dates; see announcement.

Notice of Intent to Publish a Notice of Funding Opportunity for Biomarkers of Cognitive Decline and Dementias of Aging in Individuals within the Autism Spectrum (U01 Clinical Trial Optional) (NOT-AG-2

Sponsor: National Institute on Aging

Due Date: Estimated Publication Date of Notice of Funding Opportunity: December 15, 2024. First Estimated Application Due Date: February 15, 2025.

Aging Research Dissertation Awards to Promote Diversity (R36 Clinical Trial Not Allowed) (PAR-24-130)

Sponsor: National Institute on Aging

Award: Award budgets are composed of salary and additional expenses. NIH will fund up to $42,500 per year in salary. NIH will fund up to $28,656 for additional expenses such as fringe benefits (e.g., health insurance for self and family members), travel to scientific meetings, and dissertation research costs in accordance with institutional policies. With the exception of costs associated with the dissertation (i.e., dissertation credits), no funds may be used to pay tuition or fees. Support is provided for up to two years.

Due Date: Multiple due dates; see announcement.

Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional) (PAR-25-064)

Sponsor: National Institute on Aging, National Institute of Mental Health

Award: The combined budget for direct costs for the two-year project period may not exceed $275,000, and no more than $200,000 may be requested in any single year. The maximum project period is 2 years.

Due Date: Multiple due dates; see announcement.

NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional) (PAR-25-133)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Multiple due dates; see announcement.

Digital Health Technology Derived Biomarkers and Outcome Assessments for Remote Monitoring and Endpoint Development (UG3/UH3 - Clinical Trial Optional) (PAR-25-170)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

Analytical and Clinical Validation of Biomarkers for Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (U01 Clinical Trial Optional) (PAR-25-209)

Sponsor: National Institute on Aging

Due Date: Multiple due dates; see announcement.

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) (RFA-MH-26-170)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

NINDS Exploratory Clinical Trials (UG3/UH3 Clinical Trial Required) (PAR-25-054)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: February 10, 2025. Letter of Intent due 30 days prior to application.

NINDS Ruth L. Kirschstein National Research Service Award (NRSA) for Training of Postdoctoral Fellows (F32 Clinical Trial Not Allowed) (PAR-25-234)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Multiple due dates; see announcement.