NINDS Exploratory Clinical Trials (UG3/UH3 Clinical Trial Required) (PAR-22-142)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Multiple due dates; see announcement.

Leveraging Health Information Technology (Health IT) to Address and Reduce Health Care Disparities (R01 Clinical Trial Optional) (PAR-22-145)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

Prospective Observational Comparative Effectiveness Research in Clinical Neurosciences (UG3/UH3 Clinical Trial Not Allowed) (PAR-22-076)

Sponsor: National Institute of Neurological Disorders and Stroke

Due Date: Multiple due dates; see announcement.

Technology Development Research for Establishing Feasibility and Proof of Concept (R21 - Clinical Trial Not Allowed) (PAR-22-126)

Sponsor: National Institutes of Health

Due Date: Multiple due dates, see announcement.

Focused Technology Research and Development (R01 Clinical Trial Not Allowed) (PAR-22-127)

Sponsor: National Institutes of Health

Due Date: Multiple due dates; see announcement.

NIA Program Project Applications (P01 Clinical Trial Optional) (PAR-22-130)

Sponsor: National Institute on Aging

Due Date: Multiple due dates; see announcement.

Development of Biomarkers or Biomarker Signatures for Neurological and Neuromuscular Disorders (R61/R33 Clinical Trial Optional) (PAR-22-089)

Sponsor: National Institute of Neurological Disorders and Stroke, National Institute on Aging

Due Date: Multiple due dates; see announcement.

Ultra-Rare Gene-based Therapy (URGenT) Network Resource Access (X01, Clinical Trial Not Allowed) (PAR-22-028)

Sponsor: National Institute of Neurological Disorders and Stroke.

Award: Funds are not awarded; this FOA is to provide investigators with a mechanism to access contract research/medical organizations and subject matter experts within the NINDS Ultra-Rare Gene-based Therapy (URGenT) Network to support planning, manufacturing, and limited nonclinical therapeutic development efforts.

Due Date: Multiple due dates; see announcement.

Notice of Special Interest (NOSI): Promoting research to understand vascular contributions to cognitive impairment and dementia (VCID) (NOT-HL-23-002)

Sponsor: National Heart, Lung, and Blood Institute, National Institute on Aging, National Institute of Neurological Disorders and Stroke

Due Date: This notice applies to application receipt dates on or after February 5, 2022 and subsequent receipt dates through May 8, 2025.