The center accepts brain/spinal cord and biofluid/DNA donations from participants followed in NIA- and NINDS-funded studies, within the parameters described in Toledo et al., 2013. Phenotypes include Alzheimer's disease, family history of Alzheimer's, cognitively normal, healthy normal, dementia with Lewy bodies, frontotemporal dementia, tauopathy, and Parkinson's disease. Tissue sites are whole brain, hemisphere, spinal cord, fasted CSF; samples are fixed, frozen, block, or stained.