Clonality: polyclonal
Host: Rabbit
Source: Sigma Aldrich
Cat# A2101
Reference:
Nikolev, 2009
Formulation: serum, affinity purified, phosphate buffer
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

immunogen = synthetic peptide of approximately 7-10 aa residues at the C-terminus of Aβ 43.

Specificity

Aβ cleavage site 43; cleavage site specific and its binding to the Ab peptide requires the presence of the free carboxyl group at the C- terminus of the peptide; not full length Aβ40 or Aβ 42

Comments / Questions

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References

Paper Citations

1. Nikolaev A, McLaughlin T, O'Leary DD, Tessier-Lavigne M. APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature. 2009 Feb 19;457(7232):981-9. PubMed. RETRACTED

Further Reading