Antibody
Tau (AT180)
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Clonality: monoclonal
Host: Mouse
Isotype: IgG1,κ
Source: Autogen Bioclear
cat# 90218
references:
Tatebayashi, 2002
Lewis, 2001
supplied by Innogenetics
Formulation: liquid, PBS, sterile filtered, no preservative, affinity purified, biotin
Reactivity:
Reacts in: Human
Immunogen/Epitope
immunogen = human tau40, aa. around phospho.Thr 231
Specificity
PHF tau and tau in tangles, phospho at Thr 231; weak cross with normal tau; no cross with recomb. non-phos. human tau
References
Paper Citations
- Tatebayashi Y, Miyasaka T, Chui DH, Akagi T, Mishima K, Iwasaki K, Fujiwara M, Tanemura K, Murayama M, Ishiguro K, Planel E, Sato S, Hashikawa T, Takashima A. Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13896-901. PubMed.
- Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science. 2001 Aug 24;293(5534):1487-91. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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