Antibody

Tau (AT100)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1κ
Source: Pierce Thermo Scientific
Cat# MN-1060
References:
Kosmidis, 2010
Clavaguera, 2009
Formulation: purified, no carrier or preservative
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = tau around phosphorylated Thr212 and Ser214

Specificity

PHF tau with phosphorylated Thr212 and Ser214, not normal tau, or biopsy, autopsy or fetal tau.

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References

Paper Citations

  1. Kosmidis S, Grammenoudi S, Papanikolopoulou K, Skoulakis EM. Differential effects of Tau on the integrity and function of neurons essential for learning in Drosophila. J Neurosci. 2010 Jan 13;30(2):464-77. PubMed.
  2. Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol. 2009 Jul;11(7):909-13. PubMed.

Further Reading

No Available Further Reading