Antibody

Tau (AT100)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1,κ
Source: cat# BR-012
reference
Götz, 2001
Khurana, 2006
distributed by Autogen Bioclear as 90209
Formulation: liquid, sterile filtered, PBS, no preservative
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = human PHF tau, aa. around phosphorylated Thr 212 and Ser 214

Specificity

tau phospho. at Thr 212 and Ser 214; no cross with normal tau

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References

Paper Citations

  1. Van Uden E, Mallory M, Veinbergs I, Alford M, Rockenstein E, Masliah E. Increased extracellular amyloid deposition and neurodegeneration in human amyloid precursor protein transgenic mice deficient in receptor-associated protein. J Neurosci. 2002 Nov 1;22(21):9298-304. PubMed.
  2. Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol. 2006 Feb 7;16(3):230-41. PubMed.

Further Reading

No Available Further Reading