Antibody

Tau (8E6/C11)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG
Source: anti-Tau RD3
(R. de Silva and T. Lashley, Reta Lila Weston Institute of Neurological Studies, Windeyer Building, London)
Reference:
Planel, 2008
Reactivity:
reference:<br />deSilva R, Lashley T, et al. <em>Neuropath &amp; Applied Neurobio</em> 29 (3):288, 2003

Immunogen/Epitope

peptide RS3 was designed to represent cognate regions for the 3R-tau isoforms. The RS3 sequence represents the contiguous sequences at the junction of exons 9 and 11 in the absence of exon 10

Specificity

3R-tau. No cross-reactivity was observed either at high recombinant protein concentrations or after prolonged exposure

Note

micro

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References

Paper Citations

  1. Planel E, Krishnamurthy P, Miyasaka T, Liu L, Herman M, Kumar A, Bretteville A, Figueroa HY, Yu WH, Whittington RA, Davies P, Takashima A, Nixon RA, Duff KE. Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo. J Neurosci. 2008 Nov 26;28(48):12798-807. PubMed.

Other Citations

  1. R. de Silva

Further Reading

No Available Further Reading