Antibody
Somatostatin (YC7)
Quick Links
Clonality: monoclonal
Host: Rat
Isotype: IgG2b
Source: Chemicon and Upstate are Millipore
cat# MAB354
References:
Andrews-Zwilling, 2010
Palop, 2007
Formulation: liquid, culture supernatant, thimerosal
Reactivity:
Reacts in: Rabbit, Human, Rat
Immunogen/Epitope
immunogen = synthetic 1-14 cyclic somatostatin conjugated to bovine thyroglobulin using carbodiimide
Specificity
reacts with somatostatin. Shows no cross reactivity to enkephalins, other endorphins, substance P or CGRP. Partially cross-reacts with somatostatin fragments
References
Paper Citations
- Andrews-Zwilling Y, Bien-Ly N, Xu Q, Li G, Bernardo A, Yoon SY, Zwilling D, Yan TX, Chen L, Huang Y. Apolipoprotein E4 causes age- and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice. J Neurosci. 2010 Oct 13;30(41):13707-17. PubMed.
- Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 2007 Sep 6;55(5):697-711. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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