Clonality: monoclonal
Host: Mouse
Isotype: IgG_2a
Source: NeuroMab
73-028, 75-028
from UC Davis/NIH NeuroMab Facility
References:
Lee, KJ, 2010
Stevens, 2007
Formulation: antiserum, affinity purified, PBS, azide
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

immunogen = fusion protein amino acids 77-299 of human PSD-95/SAP90 (accession
number P78352)

Specificity

recognizes the ~95-110 kDa PSD-95 protein; no cross against recombinant Chapsyn-110, SAP97 or SAP102

Comments / Questions

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References

Paper Citations

1. Lee KJ, Moussa CE, Lee Y, Sung Y, Howell BW, Turner RS, Pak DT, Hoe HS. Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines. Neuroscience. 2010 Aug 11;169(1):344-56. PubMed.
2. Stevens B, Allen NJ, Vazquez LE, Howell GR, Christopherson KS, Nouri N, Micheva KD, Mehalow AK, Huberman AD, Stafford B, Sher A, Litke AM, Lambris JD, Smith SJ, John SW, Barres BA. The classical complement cascade mediates CNS synapse elimination. Cell. 2007 Dec 14;131(6):1164-78. PubMed.

Further Reading

No Available Further Reading