Antibody
Presenilin-1, N-terminal
Quick Links
Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Calbiochem EMD Biosciences
Cat# 529591
References:
Pavlov PF, 2010
Heneka, 2010
Formulation: liquid, undiluted serum, no preservative
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat
Immunogen/Epitope
immunogen = recomb. protein containing aa 1-65 of human presenilin 1 fused to GST
Specificity
Recognizes the presenilin 1 (1-65) holoprotein and its N-terminal fragments
References
Paper Citations
- Pavlov PF, Wiehager B, Sakai J, Frykman S, Behbahani H, Winblad B, Ankarcrona M. Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein. FASEB J. 2011 Jan;25(1):78-88. PubMed.
- Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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