Clonality: monoclonal
Host: Mouse
Isotype: IgG_2a
Source: R&D Systems
Cat# MAB1458
Reference:
Pavlov PF, 2010
Formulation: filtered solution, protein-G affinity purified, PBS, trehalose, lyophilized
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = purified, E. coli-derived, recombinant human High Temperature Requirement Protein-2 (rhHtrA2; aa 134-458)

Specificity

detects the mitochondria-processed form of endogenous human HtrA2/Omi.

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References

Paper Citations

1. Pavlov PF, Wiehager B, Sakai J, Frykman S, Behbahani H, Winblad B, Ankarcrona M. Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein. FASEB J. 2011 Jan;25(1):78-88. PubMed.

Further Reading

No Available Further Reading