Antibody

Aβ fibrils (WO1)

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Clonality: monoclonal
Host: Mouse
Isotype: IgM,κ
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

raised against sonicated amyloid fibrils grown from synthesized Aβ1–40 peptides (epitope within aa 1-16)

Specificity

detects amyloid-beta fibrils; exhibits binding to fibrils in the presence of a large excess of Aβ(1–40) monomer, suggesting it is directed against conformational epitopes that only exist in the fibril

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