Clonality: monoclonal
Host: Mouse
Source: JRF/AβN/25
(Paul Mathews, New York University, School of Medicine,
Center for Dementia Research)
Paper
References:
Jiang Y., 2010
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

epitope at first 7 residues of Aβ; requires β-cleavage

Specificity

recognizes βCTF and Aβ1-X

Comments / Questions

No Available Comments

Make a comment or submit a question

To make a comment you must login or register.

References

Paper Citations

1. Jiang Y, Mullaney KA, Peterhoff CM, Che S, Schmidt SD, Boyer-Boiteau A, Ginsberg SD, Cataldo AM, Mathews PM, Nixon RA. Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1630-5. Epub 2009 Dec 28 PubMed.

External Citations

1. Paul Mathews
2. Center for Dementia Research
3. Paper

Further Reading

No Available Further Reading