Antibody

Amyloid beta[1-40]

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Clonality: kit
Host: Unknown Host
Source: IBL
cat# 27713
References:
Kitazume, 2010
Hoe, 2009
Formulation: solid phase sandwich ELISA, using 2 kinds of highly specific antibodies; range of 7.8 pg/ml ~ 500 pg/ml. Precoated plate with monoclonal 1A10, and labeled antibody 12B2
Reactivity:
Reacts in: Human

Specificity

quantitative determination of human Aβ(1-40) in EDTA-plasma, cerebrospinal fluids, serum, cell culture media or the extract from brain tissue; both recombinant and native forms of human Aβ(1-40), and little cross with (1-42) or (1-43)

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References

Paper Citations

  1. Kitazume S, Tachida Y, Kato M, Yamaguchi Y, Honda T, Hashimoto Y, Wada Y, Saito T, Iwata N, Saido T, Taniguchi N. Brain endothelial cells produce amyloid {beta} from amyloid precursor protein 770 and preferentially secrete the O-glycosylated form. J Biol Chem. 2010 Dec 17;285(51):40097-103. PubMed.
  2. Hoe HS, Lee KJ, Carney RS, Lee J, Markova A, Lee JY, Howell BW, Hyman BT, Pak DT, Bu G, Rebeck GW. Interaction of reelin with amyloid precursor protein promotes neurite outgrowth. J Neurosci. 2009 Jun 10;29(23):7459-73. PubMed.

Further Reading