Antibody

Akt phos Ser473 (587F11)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2b
Source: Cell Signaling
Cat# 4051
Reference:
Papadia, 2008
Formulation: liquid, HEPES, NaCl, BSA, glycerol, azide
Reactivity:
Reacts in: Human, Hamster, Mouse, Rat

Immunogen/Epitope

Immunogen = synthetic phospho-peptide corresp. to residues around Ser473 of mouse Akt

Specificity

reacts with endogenous Akt only when phosphorylated at Ser473; no detection of Akt phosphorylated at other sites or related kinases such as PKC and p70 S6 kinase

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References

Paper Citations

  1. Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE. Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. Nat Neurosci. 2008 Apr;11(4):476-87. PubMed.

Further Reading

No Available Further Reading