Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Calbiochem EMD Biosciences
Cat# 422751
Reference:
Kuhn, 2010
Formulation: liquid, undiluted serum, no preservative
Reactivity:
Reacts in: Human, Hamster, Mouse

Immunogen/Epitope

immunogen = synthetic peptide C-RQRPRESY
QMGHMRR corresponding to amino acids 735-749 of mouse ADAM10

Specificity

recognizes the ~98 and ~105 kDa bands corresponding to full length ADAM1O in transfected CHO-K cells, the ~60 kDa cleaved mature protein and the ~30 kDa degradation product

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References

Paper Citations

1. Kuhn PH, Wang H, Dislich B, Colombo A, Zeitschel U, Ellwart JW, Kremmer E, Rossner S, Lichtenthaler SF. ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons. EMBO J. 2010 Sep 1;29(17):3020-32. PubMed.

Further Reading

No Available Further Reading