Antibody

Actin

Tools

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Clonality: polyclonal
Host: Rabbit
Source: Sigma Aldrich
Cat# A2066
References:
Pavlov PF, 2010
Townsend, 2007
Formulation: buffered aqueous solution, PBS, BSA, azide, affinity isolated
Reactivity:
Reacts in: Various species

Immunogen/Epitope

immunogen = The C-terminal actin fragment (C11 peptide, Ser-Gly-Pro-Ser-Ile-Val -His-Arg-Lys-Cys-Phe) attached to Multiple Antigen Peptide (MAP) backbone).

Specificity

useful for studying actin structure and function and to probe binding sites of actin-binding proteins

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References

Paper Citations

  1. Pavlov PF, Wiehager B, Sakai J, Frykman S, Behbahani H, Winblad B, Ankarcrona M. Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein. FASEB J. 2011 Jan;25(1):78-88. PubMed.
  2. Townsend M, Mehta T, Selkoe DJ. Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J Biol Chem. 2007 Nov 16;282(46):33305-12. PubMed.

Further Reading

No Available Further Reading