Endoplasmic Reticulum Protein Protects Motor Neurons from ALS
Sil1’s presence keeps the endoplasmic reticulum from activating a chronic stress response.
ALL NEWS
6538 RESULTS
Sort By:
- Most Recent
- Most Commented
When Frontotemporal Dementia Leads to Crime—Prosecution or Protection?
A study reports a high incidence of criminal behavior in people with frontotemporal dementia. Especially for the undiagnosed, real trouble lies ahead.
New Parkinson’s Treatments Given Green Light
Three new therapies enhance the therapeutic effects of levodopa.
Genentech Strikes Deal with 23andMe to Study Parkinson’s Genomes
Partnership will sequence the entire genomes of 3,000 patients.
API Biomarker Data Mirror DIAN’s, Support Progression Models
Cross-sectional biomarker data from the Colombian kindred confirm models of biomarker progression, but suggest an earlier drop in brain metabolism.
Computer Model Predicts How Pathology Spreads in Alzheimer's Disease
Using baseline brain scans, the model projects where atrophy will occur and metabolism will wane.
Earliest ALS Defects Said to Start in Disparate Places
Both motor neurons in the brain and neuromuscular junctions in the periphery exhibit defects in young ALS mouse models.
Behavioral Symptoms Hit Early in Alzheimer’s
Irritability and depression emerge sooner in AD than in the general population.
Do Motor Neuron Firing Rates Rise, Then Crash, in ALS?
Neurons derived from stem cells of people with amyotrophic lateral sclerosis bungle the transmission of electrical signals.
Scientists Suggest Curbing Sugar Modification to Tame BACE
The addition of a sugar to β-secretase ramps up Aβ production. Could reducing that sweet addition slow progression of Alzheimer's?
Network Analysis Points to Distinct Effects of Amyloid, Tau
Mice with amyloid plaques develop runaway neuroinflammation, whereas mice with tau tangles predominantly lose synapses, a gene-expression study reports.
Paper Alert: Astrocyte Receptor Could Hinder Memory
People with Alzheimer’s overexpress the A2A receptor, which suppresses memory in mice.
‘Still Alice’ Gives Voice to Patients with Early Onset Alzheimer’s
Hollywood turns its attention to a rare form of dementia, giving a personal look at the impact of the disease.
Approved Amyloid Imaging Agents Work About Equally Well
All three PET agents demonstrate roughly equivalent abilities to detect brain amyloid, a new analysis finds.
Are Upper Motor Neuron Gaffes a Prelude to Disease?
Upper motor neurons, implicated in many neurodegenerative diseases, are sensitive to both cell stress and hyperexcitability.
Current Filters
No filters selected