Trontinemab Fuels Hope for Brain Shuttle Lift-Off
The transferrin receptor-targeted, anti-Aβ antibody swiftly cleared amyloid throughout the brain. It caused little ARIA, though lots of infusion reactions.
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Will We Soon Stage Alzheimer’s With Plasma Markers?
Tau fragments, alone or with other proteins, can help identify people with high tangle burden. This could help select people for trials or therapy.
Blood Tests: Not Just for the Impaired?
Real-world data hints that plasma markers can pick up Alzheimer’s pathology before people have memory complaints.
Looking Good: Immunoassays for Blood Markers
Fully automated test may be as accurate as mass spec, and more scalable
Tau PET as Progression Marker: It’s the Spread, Not the Brightness
The spatial extent of tau pathology better correlates with disease severity, and stages disease more accurately, than does tangle load.
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