Coaxing Longevity from Catalase
Mice live longer and show signs of delayed aging when they express the antioxidant enzyme...
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Mice live longer and show signs of delayed aging when they express the antioxidant enzyme...
A youth movement promotes awareness of Alzheimer’s disease and elder issues among high school and college students, as well as encourage young people to go into AD research...
A newly discovered lipid modification on the amyloid precursor protein may mark it for amyloidogenic processing...
Known for his contributions to the fundamental understanding of the tau protein, Skip Binder leaves his mark on the Alzheimer's field.
IMAGINE that: Amyloid deposition shrinks in both treatment and placebo groups, dealing a blow to the anti-aggregation drug PBT2.
A drug candidate for Alzheimer’s aims to make cell trafficking more efficient, reduce Aβ production.
An antibody against ApoE helps clear plaques and improves cognition in AD model mice.
Scientists report that astrocytes help neurons destroy their unwanted mitochondria.
The same or similar molecules might treat a variety of protein-misfolding conditions.
Cellular, animal, and human studies suggest that the AD risk gene PICALM escorts Aβ through the blood-brain barrier.
The Center for Open Science published eight guidelines for journals to boost transparency and reproducibility in research. Will journals implement them?
In a clinical trial, people who used the surgically implanted breathing-assist device died nearly a year sooner than those who used only an oxygen mask.
Researchers have generated the first atomic-level structure of γ-secretase. The new view revealed interactions between amino acid residues and the locations of familial Alzheimer’s disease mutations.
Three studies report that the C9ORF72 expansion prevents RNAs and proteins from shuttling properly between nucleus and cytosol.
The genetic relics of ancient, dormant retroviruses pepper the human genome. One such virus reanimates in about one-third of ALS cases.