Prince JA, Zetterberg H, Andreasen N, Marcusson J, Blennow K.
APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of Abeta42.
Neurology. 2004 Jun 8;62(11):2116-8.
PubMed.
One possible interpretation of this work is that transport of parenchymally secreted Abeta42 via ISF to CSF is suppressed by ApoE4. If so, it would be of particular interest to examine the effect of ApoE subtypes on CAA.
Comments
RIKEN Center for Brain Science
One possible interpretation of this work is that transport of parenchymally secreted Abeta42 via ISF to CSF is suppressed by ApoE4. If so, it would be of particular interest to examine the effect of ApoE subtypes on CAA.
Make a Comment
To make a comment you must login or register.