Antibody

p35 (C-19)

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Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Santa Cruz
Cat# sc820
References:
Ding, 2008
Rao, 2008
Ohsawa, 2008
Luo, 2007
Samuels, 2007
Formulation: affinity purified, PBS, azide; blocking peptide sc-820-P
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

immunogen = peptide mapping at the C-terminus of human p35

Specificity

reacts with p35 and p25 regulatory subunits of Cdk5; not with known cyclins

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References

Paper Citations

  1. . Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J Neurosci. 2008 Nov 5;28(45):11622-34. PubMed.
  2. . Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression. J Neurosci. 2008 Nov 19;28(47):12241-54. PubMed.
  3. . Age-dependent neurodegeneration accompanying memory loss in transgenic mice defective in mitochondrial aldehyde dehydrogenase 2 activity. J Neurosci. 2008 Jun 11;28(24):6239-49. PubMed.
  4. . Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9511-6. PubMed.
  5. . Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK. Neuron. 2007 Dec 6;56(5):823-37. PubMed.

Further Reading