All Comments by Einar Sigurdsson
- Moving Forward: RNA-Targeted Attempts at Taking Down Tau, APP
- CSF MTBR-tau-243 Tracks Tangles, Plummets in Response to Antibody
- Anti-Tau Antibody Data Leave Best Isotype Unclear
- Mounting Modifications Move Tau Toward Aggregation in Alzheimer’s Brain
- Tau: Why Alzheimer’s Worsens Fast in Some, Slowly in Others
- New Antibody Binds to Mid-Region, and Aggregates, of Tau
- Nice Catch? Antibodies Stabilize Tau in the Blood; Mark Levels in Brain
- Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement.
- Can Antibody-Based PET Scans Pinpoint Aβ Oligomers in the Brain?
- Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model.
- Transmission and spreading of tauopathy in transgenic mouse brain.
- Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.
- Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.
- A Potential Prion Therapy Focuses Attention on Protein Conversion
- Antibodies Found That Specifically Target Infectious Prions