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Webinar: Axonopathy in Mouse Models of AD

Despite the availability of a wide range of animal models of Alzheimer disease, none of them are able to fully recapitulate all the facets of the disease. Axonopathy is a case in point. Although there has been renewed interest in the link between axonal ...

Webinar: The NeuronDB Knowledge Base

Gordon Shepherd and Kei Cheung from Yale University led this Web seminar. Our featured presenters provided an introduction to SenseLab, which is a long-standing database project to build integrated multidisciplinary models of neurons and neural systems. ...

Data-mining for Medications That Affect the Incidence of Dementia

Ben Wolozin of the Boston University School of Medicine presented some results from analyzing a 4.5 million-subject database of medical records to identify medications that are associated with reduction or increase in the incidence of dementia. His team& ...

M1 Receptors Play a Central Role in AD Pathology and Cognition

Our thanks to Neuron for providing free access to this paper for the purposes of this live discussion. Caccamo A, Oddo S, Billings LM, Green KN, Martinez-Coria H, Fisher A, LaFerla FM. M1 receptors play a central role in modulating AD-like pathology in ...

An Idiosyncratic View of AD Biomarkers

Dr. Coleman led this live discussion on how biomarker information and basic science of AD can inform each other. He reviewed how the more common biomarkers of tau and Aß peptides relate to the major neurobiological deficits in AD—synaptic loss and ...

Not Dead Yet: Estrogen Deserves Another Chance

You may think the Women’s Health Study has sounded the death knell for estrogen replacement therapy, but actually, the idea is showing new signs of life. A second-generation approach with better compounds may warrant continued investment, and yet, how ...

Reducing the Risk of Alzheimer Disease

The topic is an apt one to launch the new year: what factors in daily life can reduce one's risk of Alzheimer's disease? To fire up your neural networks, you are invited to read the recent review (download pdf) by Kathryn Jedrziewski, Virginia ...

Are Glia Active Participants in Neurodegenerative Disease?

Ben Barres led the first in a series of Alzforum discussions about the role of glial cells in Alzheimer’s and other neurodegenerative diseases. It has become trendy to say that glia are more than just glue, but in reality, science has not yet advanced ...

Have a topic idea for a webinar? We would love to hear it. Send an email to webinars [at] alzforum [dot] org.

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