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Name Synonyms FDA Status Company Target Type Therapy Type Condition Approved
For
ABT-126 2 AbbVie Cholinergic System Small Molecule Alzheimer's Disease
Acitretin Soriatane ,
Neotigason,
RO 101670
2 Stiefel Laboratories, Inc. Amyloid-Related Small Molecule Alzheimer's Disease Psoriasis in US
Bexarotene Targretin® 2 Unknown Small Molecule Mild Cognitive Impairment Cutaneous T-cell Lymphoma in US
Circadin 2 Neurim Pharmaceuticals Ltd. Other Small Molecule Alzheimer's Disease Insomnia in US
EHT 0202 Etazolate 2 ExonHit Therapeutics Other Small Molecule Alzheimer's Disease None
ELND005 AZD-103,
Scyllo-inositol,
cyclohexane-1,2,3,4,5,6-hexol
2 Elan Corporation, Speranza Therapeutics Amyloid-Related Small Molecule Alzheimer's Disease None
EVP-0962 EVP 0015962 2, 2 FORUM Pharmaceuticals Inc. (was EnVivo Pharmaceuticals) Amyloid-Related Small Molecule Alzheimer's Disease, Mild Cognitive Impairment
Exendin-4 Exenatide,
Byetta,
Bydureon
2 Other Small Molecule Alzheimer's Disease Diabetes mellitus in US
G-CSF Filgrastim 2 Other Small Molecule Alzheimer's Disease Neutropenia in US
Ladostigil Hemitartrate TV-3,326 2 Avraham Pharmaceuticals Ltd Cholinergic System Small Molecule Mild Cognitive Impairment
Levetiracetam Keppra 2, Discontinued GlaxoSmithKline (GSK), Otsuka Pharmaceutical Co., Ltd., UCB S.A. Amyloid-Related, Other Small Molecule Mild Cognitive Impairment, Parkinson's Disease Epilepsy and Partial Seizures in U.S., European Union, plus about 20 other countries
Liraglutide Victoza™ 2 Novo Nordisk A/S Other Small Molecule Alzheimer's Disease
Minocycline Solodyn,
Arestin,
Minocin,
Dynacin
2 Inflammation Small Molecule Alzheimer's Disease
MK-7622 2 Merck Unknown Small Molecule Alzheimer's Disease
MSDC-0160 Mitoglitazone 2 Metabolic Solutions Development Company Other Small Molecule Alzheimer's Disease
Nasal Insulin Detemir,
Levemir,
Humulin,
Novolin
2, 2, 2, 2 Amyloid-Related, Other Small Molecule, Other Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple System Atrophy Diabetes
NIC5-15 Pinitol,
D-Pinitol
2 Humanetics Pharmaceuticals Corporation Amyloid-Related, Other Small Molecule, Dietary Supplement Alzheimer's Disease
Nicotinamide Enduramide,
Niacinamide,
Nicotinic acid amide,
Vitamin B3
2 Other Small Molecule Alzheimer's Disease
ORM-12741 2 Orion Pharma Other Neurotransmitters Small Molecule Alzheimer's Disease
PBT2 PBT-2 2, 2 Prana Biotechnology Limited Amyloid-Related, Metals Small Molecule Alzheimer's Disease, Huntington's Disease
PF-05212377 PF-5212377,
WYE-103760,
SAM-760
2 Pfizer Other Neurotransmitters Small Molecule Alzheimer's Disease
R-pramipexole RPPX,
Dexpramipexole,
KNS-760704 ,
BIIB 050
2, Discontinued Biogen Idec, Knopp Biosciences LLC, Virginia Commonwealth University Other Neurotransmitters, Other Small Molecule Alzheimer's Disease, Amyotrophic Lateral Sclerosis
Rilapladib SB-659032 2 GlaxoSmithKline (GSK) Other Small Molecule Alzheimer's Disease
Riluzole Rilutek®,
RP 54274
2, Discontinued, Approved, Discontinued Sanofi Other Neurotransmitters, Other Small Molecule Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Huntington's Disease Amyotrophic Lateral Sclerosis in many countries
SAR110894D 2 Sanofi Other Small Molecule Alzheimer's Disease
T-817MA T 817MA, T817MA 2 Toyama Chemical Co., Ltd. Other, Unknown Small Molecule Alzheimer's Disease