Therapeutics

Physostigmine Salicylate

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Overview

Name: Physostigmine Salicylate
Synonyms: Synapton
Therapy Type: Small Molecule (timeline)
Target Type: Cholinergic System (timeline)
Condition(s): Alzheimer's Disease
U.S. FDA Status: Alzheimer's Disease (Discontinued)
Company: Forest Laboratories, Inc.

Background

Physostigmine salicylate is a reversible acetylcholinesterase inhibitor that effectively increases the concentration of acetylcholine and thus the stimulation of both nicotinic and muscarinic receptors due to the increase in available acetylcholine at the synapse.

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