PAPER Stocchi F, Radicati FG, Torti M
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329960 RESULTS
Tony Fantana
Lilly
Suresh Dheerendra
LundbeckDeerfield, United States
LRRK2 Interactions Identify New Parkinson’s Genes, Implicate Autophagy
RESEARCH NEWS 2014-02-05 Research News Although the most common genetic cause of familial Parkinson’s, LRRK2 has eluded efforts to understand how it promotes disease. Now, in the February 3 Proceedings of the National Academy of Sciences, researchers led by Mark Cookson at the Na
Scott Small on Postmortem examination of patient H.M.'s brain based on histological sectioning and digital 3D reconstruction.
COMMENT This is a fascinating paper, with three main points of interest: First, it is notable that H.M. has a near-complete ablation of the entorhinal cortex, yet there is remarkable preservation of many hippocampal regions (i.e., the dentate gyrus, the CA subfie
PAPER Carter CJ
The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease.
ISRN Neurol. 2011;2011:394678. Epub 2011 Jul 12 PubMed: 22389816PAPER Sasaoka N, Sakamoto M, Kanemori S, Kan M, Tsukano C, Takemoto Y, Kakizuka A
Long-term oral administration of hop flower extracts mitigates Alzheimer phenotypes in mice.
PLoS One. 2014;9(1):e87185. Epub 2014 Jan 29 PubMed: 24489866PAPER Mhatre SD, Satyasi V, Killen M, Paddock BE, Moir RD, Saunders AJ, Marenda DR
Synaptic abnormalities in a Drosophila model of Alzheimer's disease.
Dis Model Mech. 2014 Mar;7(3):373-85. Epub 2014 Jan 30 PubMed: 24487408PAPER Piras S, Furfaro AL, Piccini A, Passalacqua M, Borghi R, Carminati E, Parodi A, Colombo L, Salmona M, Pronzato MA, Marinari UM, Tabaton M, Nitti M
Monomeric Aβ1-42 and RAGE: key players in neuronal differentiation.
Neurobiol Aging. 2014 Jun;35(6):1301-8. Epub 2014 Jan 10 PubMed: 24484607PAPER Saracchi E, Fermi S, Brighina L
Emerging candidate biomarkers for Parkinson's disease: a review.
Aging Dis. 2014 Feb;5(1):27-34. Epub 2013 Oct 9 PubMed: 24490114PAPER Ducas VC, Rhoades E
Investigation of intramolecular dynamics and conformations of α-, β- and γ-synuclein.
PLoS One. 2014;9(1):e86983. Epub 2014 Jan 28 PubMed: 24489820PAPER Neuner J, Filser S, Michalakis S, Biel M, Herms J
A30P α-Synuclein interferes with the stable integration of adult-born neurons into the olfactory network.
Sci Rep. 2014 Feb 3;4:3931. PubMed: 24488133PAPER Escobar VD, Kuo YM, Orrison BM, Giasson BI, Nussbaum RL
Transgenic mice expressing S129 phosphorylation mutations in α-synuclein.
Neurosci Lett. 2014 Mar 20;563:96-100. Epub 2014 Jan 30 PubMed: 24486885PAPER Su XW, Broach JR, Connor JR, Gerhard GS, Simmons Z
Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research.
Muscle Nerve. 2014 Jun;49(6):786-803. Epub 2014 Apr 8 PubMed: 24488689PAPER Kryściak K, Grieb P, Celichowski J
Changes in motor unit properties in SOD1 (G93A) rats.
Muscle Nerve. 2014 Feb 1; PubMed: 24488615Current Filters
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