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C9ORF72’s Dirty Work Done by Problem Proteins
RESEARCH NEWS 2014-08-11 Research News Hexanucleotide repeat expansions in the C9ORF72 gene are the leading genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis, but alas, researchers do not know whether these repeats wreak havoc by way of wonky RNA molecule
PAPER Mizielinska S, Grönke S, Niccoli T, Ridler CE, Clayton EL, Devoy A, Moens T, Norona FE, Woollacott IO, Pietrzyk J, Cleverley K, Nicoll AJ, Pickering-Brown S, Dols J, Cabecinha M, Hendrich O, Fratta P, Fisher EM, Partridge L, Isaacs AM
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.
Science. 2014 Sep 5;345(6201):1192-1194. Epub 2014 Aug 7 PubMed: 25103406PAPER Mohan A, Goodwin M, Swanson MS
RNA-protein interactions in unstable microsatellite diseases.
Brain Res. 2014 Apr 4; PubMed: 24709120Gao Li
Minjiang UniversityChina
Stem Cells Grown From 86-Year-Old Man Morph into Neurons in Rat Spinal Cord
RESEARCH NEWS 2014-08-11 Research News It may be hard to believe, but according to a paper in the August 7 issue of the journal Neuron, neural stem cells grown from an old man underwent dramatic rebirth when grafted into injured rat spinal cords. Reportedly, the cells generated n
PAPER Lu P, Woodruff G, Wang Y, Graham L, Hunt M, Wu D, Boehle E, Ahmad R, Poplawski G, Brock J, Goldstein LS, Tuszynski MH
Long-Distance Axonal Growth from Human Induced Pluripotent Stem Cells after Spinal Cord Injury.
Neuron. 2014 Aug 6; PubMed: 25123310PAPER Tuszynski MH, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Lu P
Neural stem cells in models of spinal cord injury.
Exp Neurol. 2014 Jul 28; PubMed: 25079369PAPER Sharp KG, Yee KM, Steward O
A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury.
Exp Neurol. 2014 Jul;257:186-204. Epub 2014 Apr 18 PubMed: 24747827PAPER Lu P, Kadoya K, Tuszynski MH
Axonal growth and connectivity from neural stem cell grafts in models of spinal cord injury.
Curr Opin Neurobiol. 2014 Aug;27C:103-109. Epub 2014 Apr 5 PubMed: 24709371PAPER Lu P, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Tuszynski MH
Long-distance growth and connectivity of neural stem cells after severe spinal cord injury.
Cell. 2012 Sep 14;150(6):1264-73. PubMed: 22980985Dana Brunetti
Dulce Papy-Garcia
Université Paris Est CreteilCreteil, France
PAPER Li P, Tong C, Mehrian-Shai R, Jia L, Wu N, Yan Y, Maxson RE, Schulze EN, Song H, Hsieh CL, Pera MF, Ying QL
Germline competent embryonic stem cells derived from rat blastocysts.
Cell. 2008 Dec 26;135(7):1299-310. PubMed: 19109898PAPER Buehr M, Meek S, Blair K, Yang J, Ure J, Silva J, McLay R, Hall J, Ying QL, Smith A
Capture of authentic embryonic stem cells from rat blastocysts.
Cell. 2008 Dec 26;135(7):1287-98. PubMed: 19109897Current Filters
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