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David Holtzman on In AD, CSF Immune Cells Hint at Mounting Mayhem in the Brain
COMMENT In this interesting resource paper by Piehl et al. from the lab of David Gate, the authors assess the CSF immune cell profiles of 45 cognitively normal subjects and 14 cognitively impaired subjects who likely had very mild to mild Alzheimer’s disease. Usi
PAPER Wei J, Ge K, Gong Y, Li L, Tang Q, Liao X, Zhang G, Gao F
DNAzyme-driven bipedal DNA walker for label-free and signal-on electrochemical detection of amyloid-β oligomer.
Int J Biol Macromol. 2023 Feb 15;228:234-241. Epub 2022 Dec 22 PubMed: 36566812PAPER Bonvicini G, Syvänen S, Andersson KG, Haaparanta-Solin M, López-Picón F, Sehlin D
ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein.
Transl Neurodegener. 2022 Dec 26;11(1):55. PubMed: 36567338PAPER Dai J, Xu Y, Wang T, Zeng P
Exploring the relationship between socioeconomic deprivation index and Alzheimer's disease using summary-level data: From genetic correlation to causality.
Prog Neuropsychopharmacol Biol Psychiatry. 2023 Apr 20;123:110700. Epub 2022 Dec 22 PubMed: 36566903PAPER Wang F, Pritzkow S, Soto C
PMCA for ultrasensitive detection of prions and to study disease biology.
Cell Tissue Res. 2023 Apr;392(1):307-321. Epub 2022 Dec 26 PubMed: 36567368PAPER Ali MU, Anwar L, Ali MH, Iqubal MK, Iqubal A, Baboota S, Ali J
Signalling Pathways Involved in Microglial Activation in Alzheimer's Disease and Potential Neuroprotective Role of Phytoconstituents.
CNS Neurol Disord Drug Targets. 2022 Dec 23; PubMed: 36567300PAPER Ng W, Ng SY
Remodeling of astrocyte secretome in amyotrophic lateral sclerosis: uncovering novel targets to combat astrocyte-mediated toxicity.
Transl Neurodegener. 2022 Dec 26;11(1):54. PubMed: 36567359PAPER Sharma M, Burré J
α-Synuclein in synaptic function and dysfunction.
Trends Neurosci. 2023 Feb;46(2):153-166. Epub 2022 Dec 23 PubMed: 36567199PAPER Yin KJ, Hamblin MH, Lee JP
Editorial of special issue: Pharmacological, gene, and cell-based therapeutics targeting early or late neurodegenerative and neurovascular diseases.
Exp Neurol. 2023 Mar;361:114297. Epub 2022 Dec 13 PubMed: 36566701PAPER Amin AM, Mostafa H, Khojah HM
Insulin resistance in Alzheimer's disease: The genetics and metabolomics links.
Clin Chim Acta. 2023 Jan 15;539:215-236. Epub 2022 Dec 22 PubMed: 36566957PAPER Fronza MG, Sacramento M, Alves D, Praticò D, Savegnago L
QTC-4-MeOBnE Ameliorated Depressive-Like Behavior and Memory Impairment in 3xTg Mice.
Mol Neurobiol. 2023 Mar;60(3):1733-1745. Epub 2022 Dec 26 PubMed: 36567360PAPER Javed H, Mohamed Fizur NM, Jha NK, Ashraf GM, Ojha S
Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer's and Parkinson's Diseases.
Curr Neuropharmacol. 2023;21(6):1421-1432. PubMed: 36567278PAPER Neupane S, De Cecco E, Aguzzi A
The Hidden Cell-to-Cell Trail of α-Synuclein Aggregates.
J Mol Biol. 2023 Jun 15;435(12):167930. Epub 2022 Dec 22 PubMed: 36566800PAPER Kleschevnikov A
GIRK2 Channels in Down syndrome and Alzheimer's disease.
Curr Alzheimer Res. 2022 Dec 23; PubMed: 36567290Current Filters
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