RESEARCH NEWS 2014-10-24 Research News Could infectious agents hold the key to treating neurodegenerative disease? The idea may not be as crazy as it sounds. Some neuropathogens have evolved ways to turn off cell death mechanisms to keep their hosts alive. The same approach might ...
PAPER Berthet A, Margolis EB, Zhang J, Hsieh I, Zhang J, Hnasko TS, Ahmad J, Edwards RH, Sesaki H, Huang EJ, Nakamura K25339743
Disha Shah on Early alterations in functional connectivity and white matter structure in a transgenic mouse model of cerebral amyloidosis.
COMMENT Grandjean and colleagues used resting-state functional MRI (rsfMRI) techniques in ArcAβ and wild-type mice at different time points across their lifespan to investigate the relation between functional connectivity disruptions and amyloid pathology. They ...
PAPER Li Y, Song W, Wu J, Zhang Q, He J, Li A, Qian J, Zhai A, Hu Y, Kao W, Wei L, Zhang F, Xu D23702035
PAPER Poenisch M, Burger N, Staeheli P, Bauer G, Schneider U
Protein X of Borna disease virus inhibits apoptosis and promotes viral persistence in the central nervous systems of newborn-infected rats.J Virol. 2009 May;83(9):4297-307. Epub 2009 Feb 11 PubMed: 19211764
PAPER Miranda HC, Nunes SO, Calvo ES, Suzart S, Itano EN, Watanabe MA
Detection of Borna disease virus p24 RNA in peripheral blood cells from Brazilian mood and psychotic disorder patients.J Affect Disord. 2006 Jan;90(1):43-7. Epub 2005 Dec 1 PubMed: 16324750
PAPER Szelechowski M, Bétourné A, Monnet Y, Ferré CA, Thouard A, Foret C, Peyrin JM, Hunot S, Gonzalez-Dunia D
A viral peptide that targets mitochondria protects against neuronal degeneration in models of Parkinson's disease.Nat Commun. 2014 Oct 21;5:5181. PubMed: 25333748
RESEARCH NEWS 2014-10-24 Research News Neural circuits go on the fritz in Alzheimer’s disease, but how that relates to underlying disease mechanisms is unclear. Researchers have identified dysfunctional circuits in the AD brain using magnetic resonance imaging, but they cannot ...
PAPER Jonckers E, Van Audekerke J, De Visscher G, Van der Linden A, Verhoye M
Functional connectivity fMRI of the rodent brain: comparison of functional connectivity networks in rat and mouse.PLoS One. 2011 Apr 18;6(4):e18876. PubMed: 21533116
PAPER Adamczak JM, Farr TD, Seehafer JU, Kalthoff D, Hoehn M20211267
PAPER Nair G, Duong TQ15282829
PAPER Ahrens ET, Dubowitz DJ11477652
PAPER Liang Z, King J, Zhang N21389232
PAPER Grandjean J, Schroeter A, Batata I, Rudin M
Optimization of anesthesia protocol for resting-state fMRI in mice based on differential effects of anesthetics on functional connectivity patterns.Neuroimage. 2014 Aug 28;102P2:838-847. PubMed: 25175535
RESEARCH NEWS 2014-10-24 Research News Dozens of mutations in the gene for superoxide dismutase 1 can cause amyotrophic lateral sclerosis, and they all do so by making the normally rigid enzyme floppy and aggregation-prone, according to a paper in the October 14 Proceedings of ...
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