Elizabeth Head on Down’s Syndrome Loosens Regulation of the Entire Genome
COMMENT Fascinating! elizabeth.head 0
330986 RESULTS
COMMENT Fascinating! elizabeth.head 0
COMMENT This is a very carefully done study that combines elegant structural biology, drug discovery, cell biology, and neuroscience. Clearly, endosomal APP is an attractive target and the authors of the study have identified a pharmacological chaperone that stab
Neurology
Biogen Idec
CONFERENCE 2014-04-26 00:00:00-2014-05-03 00:00:00 Philadelphia, Pennsylvania, U.S.A. 26 April 2014 to 03 May 2014 View Conference Website 1
Houston, United States
PAPER Yang YJ, Baltus AE, Mathew RS, Murphy EA, Evrony GD, Gonzalez DM, Wang EP, Marshall-Walker CA, Barry BJ, Murn J, Tatarakis A, Mahajan MA, Samuels HH, Shi Y, Golden JA, Mahajnah M, Shenhav R, Walsh CA
COMMENT The authors analyzed gene expression differences (transcriptome differences) in a pair of monozygotic twins in which only one (T1DS) had Down’s syndrome. Gene expression was analyzed in fetal fibroblasts and in pluripotent stem cells derived from fibrobla
PAPER Azimova RK, Kagan BL
grenoble, France
PAPER Yesuvadian R, Krishnamoorthy J, Ramamoorthy A, Bhunia A
PAPER Liu P, Sun L, Zhao XL, Zhang P, Zhao XM, Zhang J
PAPER Savolainen MH, Richie CT, Harvey BK, Männistö PT, Maguire-Zeiss KA, Myöhänen TT
PAPER Pasanen P, Myllykangas L, Siitonen M, Raunio A, Kaakkola S, Lyytinen J, Tienari PJ, Pöyhönen M, Paetau A
PAPER Hardy J, Bogdanovic N, Winblad B, Portelius E, Andreasen N, Cedazo-Minguez A, Zetterberg H
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