PAPER Liew Z, Wang A, Bronstein J, Ritz B
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PAPER Sawada H, Oeda T, Umemura A, Tomita S, Hayashi R, Kohsaka M, Yamamoto K, Sudoh S, Sugiyama H
Subclinical elevation of plasma C-reactive protein and illusions/hallucinations in subjects with Parkinson's disease: case-control study.
PLoS One. 2014;9(1):e85886. Epub 2014 Jan 31 PubMed: 24497930PAPER Wong JC, Li Y, Schwarzschild MA, Ascherio A, Gao X
Restless legs syndrome: an early clinical feature of Parkinson disease in men.
Sleep. 2014 Feb 1;37(2):369-72. PubMed: 24497665PAPER Sand PG, Welz T
PITX3 variants in Chinese patients with Parkinson's disease.
Swiss Med Wkly. 2014 Feb 4;144:w13702. PubMed: 24496700PAPER Rocha NP, Scalzo PL, Barbosa IG, de Sousa MS, Morato IB, Vieira EL, Christo PP, Reis HJ, Teixeira AL
Circulating levels of adipokines in Parkinson's disease.
J Neurol Sci. 2014 Apr 15;339(1-2):64-8. Epub 2014 Jan 23 PubMed: 24495872PAPER Lilleeng B, Brønnick K, Toft M, Dietrichs E, Larsen JP
Progression and survival in Parkinson's disease with subthalamic nucleus stimulation.
Acta Neurol Scand. 2014 Feb 4; PubMed: 24495107PAPER Armstrong RA
Cortical degeneration in frontotemporal lobar degeneration with TDP-43 proteinopathy caused by progranulin gene mutation.
Int J Neurosci. 2014 Mar 3; PubMed: 24494724Jenny Gunnersen
The University of MelbourneParkville, Australia
Walter J. Schulz-Schaeffer on Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease.
COMMENT This paper by Spinelli et al. fits well in my concept that presynaptic alpha-synuclein aggregates are pathophysiologically linked to the diseases PD, PDD, and DLB. It’s interesting to know that in-vivo multiphoton imaging may be able to monitor presynapti
Subhojit Roy on Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease.
COMMENT These studies from Vivek Unni’s lab reiterate the importance of focusing on the synaptic accumulation and aggregation of α-synuclein, rather than somatic Lewy bodies. Specifically, they strengthen the hypothesis that small increments in α-synuclein are de
Alpha-Synuclein Types Congregate in Presynapse—Which Is the Bad One?
RESEARCH NEWS 2014-02-07 Research News Alpha-synuclein shape-shifts in synaptic terminals, according to a study that tracked the protein’s movements in the neurons of living mice. Published February 5 in The Journal of Neuroscience, the findings showed that while free α-synuclein
PAPER Rizo J, Südhof TC
The membrane fusion enigma: SNAREs, Sec1/Munc18 proteins, and their accomplices--guilty as charged?
Annu Rev Cell Dev Biol. 2012;28:279-308. PubMed: 23057743PAPER Spinelli KJ, Taylor JK, Osterberg VR, Churchill MJ, Pollock E, Moore C, Meshul CK, Unni VK
Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease.
J Neurosci. 2014 Feb 5;34(6):2037-50. PubMed: 24501346Grants to Explore Boundaries Between Alzheimer’s and Parkinson’s
COMMUNITY NEWS 2014-02-07 Community News What do Alzheimer’s disease and Parkinson’s have in common, and what makes them unique? A new funding opportunity encourages researchers to re-examine the question. Biomarkers Across Neurodegenerative Diseases—BAND for short—will offer gran
Anna Tury
UC San DiegoLa Jolla, United States
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